Pharmacokinetics between Pediatric and Geriatrics

The main difference paediatric and geriatrics is age-related difference and changes in physiochemical factors based on age group and body conditions. Therefore the anatomical, physiological and biochemical changes occurring throughout varies age groups are studies  because these affect the pharmacokinetic and pharmacodynamics effect which further influence the bioavailability if drugs and bio disposition of then in the body . The major differences using drugs is about routes of administration of drugs and the permeability of drug through various membrane and drug biotransformation capability and the way that are excreted is known. The changes in chromosomal and gene levels are mainly studied for better therapy.

 

  • Bioavailability
  • Bio disposition
  • Drug metabolism & pharmacokinetics (DMPK)
  • Physiochemical factors that are affecting

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